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doi:10.1007/s13353-016-0380-3 108
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Be alert for signs of hypersensitivity reactions like anaphylaxis and angioedema, which have been reported in some cases
This built-in opponent regulation means that the melanocortin system functions as a balanced agonist/antagonist system, and pharmacological agonists like MT-2 and PT-141 compete with AgRP and agouti for receptor access
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