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The complexity of A549 cell extract (and cell extracts generally) as a matrix precludes the use of a commercially available matrix that replicates its composition without containing endogenous analytes and cellular debris, making conventional external calibration challenging for addressing matrix effects
The same trained evaluator assessed all subjects under controlled conditions at both baseline and Week 12 ensuring consistent, unbiased scoring
Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels
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