glp-1 rheumatoid arthritis study 1 — Curr Opinion in Rheumatology (2026 Review, U of Michigan), https://pubmed.ncbi.nlm.nih.gov/41782546/, Study 2 — ACR Open Rheumatology (2025, UCLA, N=215), Landmark randomized trials have shown

However, compounded versions are not FDA-approved in the traditional sense

Independent testing and MHRA enforcement activity (including Operation Pangea) have found that many such products contain incorrect concentrations, impurities, or in some cases entirely different substances to those labelled

Patients who are pregnant, nursing, or have severe renal impairment should consult their healthcare provider before initiating high-dose amino acid therapy

Among patients with UC, those treated with GLP1RA had lower rates of corticosteroid use (46.6% vs 85.1%), hospitalization (40.9% vs 65.9%), intestinal resection (6.52% vs 20.8%), and mortality (4.6% vs 22%) compared with controls