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The following day, overnight cultures were back-diluted 1:100 into prewarmed DRM supplemented with 50 g ml 1 spectinomycin

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POPs are mainly excreted through conjugation with GSH and this mechanism is extremely important for the health status, since exposure to POPs has been associated to diabetes, cardiovascular diseases and many other chronic diseases ( ROS production can occur at several intracellular sites but, for most cells, takes place in the mitochondria and the mitochondrial electron transport chain is the main cellular process of ROS generation in physiological circumstances ( 2 O 2 )

It can offer a more conservative entry point for patients who want appetite and metabolic support without immediately pursuing a more intensive titration schedule