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10.1194/jlr.r018689 16
Although lifestyle interventions (low-calorie diets and exercise) are still the cornerstone of weight management, weight loss achieved through this approach is extremely difficult to sustain in the long term, particularly due to physiological adaptations that reduce the energy expended or increase appetite to compensate for the missing calories
Innanzitutto, gli strumenti utilizzati negli studi, come la DXA, misurano la massa magra, che non coincide esclusivamente con il muscolo: comprende anche acqua, glicogeno, organi e altri tessuti privi di grasso
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