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Clinical studies like the SURPASS trial series compared tirzepatide and semaglutide , and their results helped clarify how dual versus single incretin therapy affects outcomes
The main ingredient, semaglutide, helps your body manage type 2 diabetes in several key ways: it signals your pancreas to release more insulin when your blood sugar is high, it reduces the amount of sugar your liver produces, and it slows down how quickly food leaves your stomach
Injectable GLP-1 therapies have faced persistent challenges in real-world settings, including supply shortages, high monthly costs, and discontinuation rates linked to side effects and needle aversion
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