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These medicationsincluding semaglutide (injectable Ozempic, oral Rybelsus, injectable Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)mimic the action of endogenous GLP-1 while resisting degradation by the enzyme dipeptidyl peptidase-4 (DPP-4)
This led the authors to speculate that Fusobacteria increased as a protection mechanism against ammonia toxicity in the intestine, although the mechanism remains unclear
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