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However, the lasting effects of these injections can vary significantly between individuals, influenced by factors such as overall health, the severity of the deficiency, and the bodys absorption capacity

The FDA guidance on subcutaneous peptide formulations acknowledges this source of pharmacokinetic variability

Considering the growing evidence supporting the effectiveness of oral vitamin B12 supplements, they may be a viable alternative to injections for many individuals

[131] [132] Species from the following genera and the following individual species are known to synthesize B 12 : Propionibacterium shermanii , Pseudomonas denitrificans , Streptomyces griseus , Acetobacterium , Aerobacter , Agrobacterium , Alcaligenes , Azotobacter , Bacillus , Clostridium , Corynebacterium , Flavobacterium , Lactobacillus , Micromonospora , Mycobacterium , Nocardia , Proteus , Rhizobium , Salmonella , Serratia , Streptococcus and Xanthomonas