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Normalization of data to an internal standard was performed using an in-house R script, then values were normalized to protein content per treatment condition
References 1 and 2 are classic papers describing both the general nature of the oxygen effect in reducing radiation sensitivity (reference 2) and the fact that the hypoxic cells almost certainly are present in human tumours (reference 1)
Dihexa is not FDA-approved and is sold only by research peptide suppliers
Targeting tumour angiogenesis with small molecule inhibitors of hypoxia inducible factor
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