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Summary: GLP-1 medications slow gut motility and gastric emptying, leading to harder stools and constipation, which can be managed through increased dietary fibre, adequate hydration, regular physical activity, and appropriate laxative use when necessary
The relationship between physical activity and mental health in a sample of the UK public: A cross-sectional study during the implementation of COVID-19 social distancing measures
This mechanism becomes clinically important when using high-dose oral supplements (typically 1000 micrograms or more), as it can provide adequate absorption even when the intrinsic factor pathway is impaired
"Hy's law"
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