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While the standard adult RDA is approximately 2.4 mcg per day (ICMR-NIN, 2024), the demands of pregnancy and breastfeeding raise this further, as the baby draws on maternal stores directly via the placenta and then through breast milk

For the primary efficacy analysis of actimetry and home diary outcomes, the outcome values were calculated using the measures performed during the planned weeks of assessment (the first and last week of each treatment period) without deviations from the target oral l-dopa dose (that is, a week when the patient did not receive the oral optimized l-dopa dose determined in phase 1 of the DIVE-1 study)

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Since 2023, there has been a worldwide shortage of GLP-1 receptor agonists, which is expected to continue until late 2024 [71]