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The patients who do best on this molecule, if it ever reaches the clinic, may be the ones whose GLP-1R and GIPR variants both fall on the responder side
These include very long term effects beyond ten years, outcomes in younger populations who may use GLP-1s for decades, effects on bone health in older adults, and rare side effects that may only appear with widespread use over time
Although weight loss medication can help, its not a quick fix for obesity
Although the NIC guidance on cannabis-based medicinal products allows for their prescription when there is an unmet clinical need related to chronic pain, CBD, alone or combination with THC, is not suggested for administration unless part of clinical trials [277]
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