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The favorable cardiovascular profile of the GLP-1RA class was reinforced by SURPASS-CVOT, in which the dual GIP/GLP-1 receptor agonist tirzepatide was noninferior to dulaglutide, an agent with established cardiovascular benefit, for three-point MACE in patients with type 2 diabetes and ASCVD [40]
They both are USP meaning they have an official monograph or documentation by the United States Pharmacopeia, both are not used for IV solutions
Melanotan 2 has no standardized clinical dosing protocol this is a community protocol based on decades of underground use and limited clinical data
Elsevier 2011)
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