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For really bad cases, you might need more, and shots are given once a week, or as the doctor says
With only a brief analysis of B12 requirements, they recommend vegetarians take a supplement of 250 g per day (Pawlak, 2013)
But B12 is involved in complex body wide set of interactions
[1] Other rare side effects noted (mostly in older literature or high-dose use) include: polycythemia vera and peripheral vascular thrombosis in patients receiving repeated injections (though these associations are not well understood, they were listed in prior product literature as possible adverse events)
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