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Recent literature suggests that central GLP-1 and GIP have a synergistic action on hypothalamic neurons with effects on food intake and body weight (24) ( Figure 2 )

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More recently, secukinumab, an interleukin (IL)-17A inhibitor, and bimekizumab, an IL-17A and IL-17F inhibitor, have been approved for the treatment of moderate to severe HS (1012)

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