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The stimulant effects of phentermine (increased heart rate, elevated blood pressure) combined with the cardiovascular changes produced by GLP-1 medications created a physiological profile that researchers flagged for further investigation

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Many people report that food no longer drives their thoughts or behavior in the same way. In 2012, Skibickas lab was the first to demonstrate reduced alcohol reward and motivation in animal models treated with a GLP-1 analog

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