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doi: 10.3389/fmolb.2022.925700

But in practice, and especially with regard to synthetic and recombinant peptide forms, there are some considerable potential safety concerns: Immunogenicity Most notably, per a 2020 assessment on therapeutic peptide safety, synthetic and recombinant peptides pose the risk of immunogenicity the ability of a substance to provoke an immune response.15 An immunogenicity-inducing peptide, when introduced to the body, would cause the bodys immune system to perceive the peptide not as a medication but as a threat

state that despite a paucity of supporting evidence, many experts will tolerate a few daily seizures to mitigate the risk of complications associated with profound sedation. (38117319) [#4] lift sedation to determine if seizures can be controlled off anesthetic infusions Anesthetic infusions are weaned off (while continuing maintenance antiseizure medications)