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This is not a general wellness recommendation
Conclusion It is entirely possible to lose weight effectively without GLP-1 agonists by relying on natural methods such as a healthy diet, regular physical activity, and thoughtful lifestyle changes
GLP-1 Receptor (GLP-1R) Agonism Stimulates glucose-dependent insulin secretion: Enhances pancreatic beta-cell insulin release, thus lowering blood glucose 1,3,4
However, 10 PWS patients showed no significant changes in BMI, weight z -score, and ghrelin when the effectiveness was measured after 6 months of exenatide use, even though improved HbA1c level and decreasing appetite scores were noted [12]
