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The article repeatedly notes that individual response varies substantially

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In addition, EDV regulates the hypothalamicpituitaryadrenal (HPA) axis via downregulation of FK506 binding protein 5 (FKBP5), a protein involved in glucocorticoid receptor (GR) trafficking to the nucleus, which may contribute to normalization of stress-induced abnormalities in the HPA axis (Herbet et al., 2019)