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High levels of cytoplasmic tyramine result in its transport into vesicles via VMAT2, displacing stored vesicular norepinephrine into the neuronal cytoplasm, resulting in an increase of cytoplasmic norepinephrine (Raiteri and Levi, 1986
Flotillin microdomains interact with the cortical cytoskeleton to control uropod formation and neutrophil recruitment
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In addition, other microbiota-related alterations, including disturbed tryptophan metabolism and abnormal fermentation, may further shape IBS symptom patterns [270, 275]
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