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Description

Cycloheximide (CHX), tunicamycin (TUN), 6-diazo-5-oxo-L-norleucine (DON), reduced L-glutathione (GSH), reduced glutathione ethyl ester (GSHee) were from Sigma-Aldrich (St

[Abstract]2025 Dec;333(Pt 1):148831

CrAT deficiency leads to accumulating acetyl-CoA, which exerts an allosteric inhibiting effect on pyruvate dehydrogenase (PDH), a rate-limiting enzyme for pyruvate entry into the Krebs cycle