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However, inherent methodological limitationsincluding potential confounding, exposure misclassification, and population heterogeneityconstrain causal inference from human data alone and therefore warrant cautious interpretation of these findings
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For individuals with severe B12 deficiency (especially those with anaemia or neurological symptoms), some might start to feel an improvement in their energy levels within a few days to a week
Policymakers are being asked to make consequential regulatory decisions, while some emerging therapies show promise but have scarce human safety data
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