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The underlying mechanisms involve stimulating genes such as Egr 1, NAB2, FAK paxillin, and JAK 2 pathways [8]

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230 This modification can improve the resistance of nucleic acids to nucleases, enhance blood stability, reduce renal clearance, and prolong the circulation time of drugs in vivo by improving their binding to plasma proteins

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Underlying mechanisms Gastrointestinal adverse events associated with GLP-1 RAs reflect altered gastrointestinal function

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Clinical studies have shown that Tirzepatide can result in substantial weight loss by suppressing appetite and enhancing insulin sensitivity

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