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Here we demonstrate a critical role for the RNA-binding protein SFPQ in preventing aberrant R-loop formation across a broad spectrum of repetitive elements, including pericentromeric and centromeric satellite repeats, subtelomeres, telomeres, as well as LINE-1 and SINE elements
However, this generally isnt a major problem (more on this below)
doi: 10.1016/j.blre.2020.100676 315
Tsushima M, Liu J, Hirao W, Yamazaki H, Tomita H, Itoh K
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