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Human mutation, 13(5), 362375.[PubMed] [Wiley] Lalouschek, W., Aull, S., Serles, W., Schnider, P., Mannhalter, C., Lang, T., Deecke, L., & Zeiler, K
Wu H, Esteve E, Tremaroli V et al (2017) Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
It may allow the broader treatment to be used more fully
Our animal models, induced using endothelin-1 (ET-1), reflect clinically relevant cerebral I/R conditions yet may not fully capture the complexity of human pathophysiology, including inter-individual anatomical variation and comorbidities ( in vivo , including their potential off-target effects and clearance pathways
