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Specifically, eligible studies included participants (P) with a confirmed diagnosis of vitamin B12 deficiency, interventions (I) involving oral or sublingual vitamin B12 administration, comparators (C) using intramuscular supplementation, and outcomes (O) reporting changes in serum vitamin B12 or homocysteine levels

However, people with genetic irregularities or other health conditions causing a lack of L-carnitine should talk with their doctor for a more specific dosage

* Based on people who continued treatment as intended in the 72-week ATTAIN-1 trial, alongside exercise and a healthy, balanced diet

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