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It does not activate GLP-1 receptors directly
Zepbound is FDA-approved for chronic weight management in obesity (body mass index of 30 or more) or overweight (body mass index of 27 or more) with at least one weight-related condition (such as high blood pressure, type 2 diabetes or high cholesterol) in addition to a low-calorie diet and exercise
Specifically, in the group of patients prescribed semaglutide for weight loss, 6.7% developed NAION compared to just 0.8% of those on other treatments
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