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Theres no compiled clinical trial data similar to the liraglutide analysis, and most women who became pregnant during semaglutide trials stopped the medication immediately upon discovery

For semaglutide , it depends on how its prescribed: Wegovy : A BMI of 30 or higher or a BMI of 27 or higher with at least one weight-related condition, like high blood pressure or high cholesterol Used alongside lifestyle changes for long-term weight management For retatrutide , again, there are no official prescribing rules yet

For research outcomes that depend on precise dosing (IGF-1 LR3 dose-response curves are steep in most anabolic and metabolic study designs), even small volumetric errors compound across a multi-week protocol

That effect can be helpful for some people but risky for others, especially during dehydration, hot weather, vomiting, or reduced fluid intake