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The structural basis for this stability is not fully elucidated but may relate to its high proline content (3 consecutive Pro residues) which confers rigidity and protease resistance

The samples were then incubated with the equilibration buffer provided in the TUNEL assay kit at room temperature for 10 min, followed by incubation with the reaction mixture containing terminal deoxynucleotidyl transferase and labeled dUTP

Ros, cell senescence, and novel molecular mechanisms in aging and age-related diseases