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In CKD patients, even though anemia develops primarily as a result of the decreased lifespan of RBCs caused by the low production of erythropoietin and iron deficiency, eryptosis seems to be a fundamental contributing factor [244,245,246]
Over the past 20 years, dozens of preclinical studies (in animals and cells, not humans) have shown potentially promising data suggesting the peptide can fight inflammation and promote protein synthesis and angiogenesisthe fancy scientific term for new blood vessel production
With the RGD-mediated affinity with cancer cells, the nanocomposite (GOx-CuCaP@MNSs-MET@PEG-RGD, GCMMR) could accomplish targeting delivery and TME-activated release of cargos
Unlike the recombinant growth hormone, it doesnt raise GH in the body to supraphysiological levels
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