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The only treatment that has consistently demonstrated long-term success in managing obesity is metabolic surgery, says Tyler Cohn, MD, interim director, division of minimally invasive, bariatric and community general surgery at Loyola Medicine
While studies in mice indicate the potential direct benefits of GLP-1 on the skeletal muscle and bone, human data supporting this hypothesis are absent owing to the absence of GLP-1 receptors in the human skeletal muscle, implying that any effects on muscles are likely indirect [114]
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