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Findings presented at the Clinical Trials on Alzheimers Disease 2025 Congress in San Diego in December 2025 from the EVOKE and EVOKE+ Phase III studies evaluating oral semaglutide in early Alzheimers disease did not meet the main cognitive endpoint despite biomarker signals underscoring the translational gap between metabolic modulation and the complex nature of neurodegenerative processes

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If the provider documents peripheral neuropathy, distal symmetric polyneuropathy, or stocking-glove distribution, E11.42 is the appropriate code