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They work by mimicking the GLP-1 hormone, which: Stimulates insulin secretion in a glucose-dependent manner Suppresses glucagon release Slows gastric emptying Reduces appetite by acting on receptors in the brain It is important to note that Wegovy (semaglutide 2.4 mg) is the formulation licensed for weight management in the UK
Stacking two appetite-active compounds can amplify them, which is the single biggest tolerability concern with any cagrilintide-plus-tirzepatide concept
10.3390/metabo13070793 9 D'AlessandroA.EarleyE
Benveniste H, Liu X, Koundal S, Sanggaard S, Lee H, Wardlaw J
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