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Interestingly, we found that succinate accumulated only in Gclc- deficient B cells and not in Gclc- deficient effector T cells nor Tregs 43,44

When to see a Dermatologist

Zhao, Xin et al

In addition, altered metabolite concentrations after glucose administration also influence multiple metabolic pathways including glycolysis, gluconeogenesis, glycogenesis, amino acid metabolism, and lipid metabolism by regulating the abundance of substrates and products and the allosteric regulation of metabolic enzymes 14,16,17,18