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Description

The 8mg dose achieved 22.8% body weight reduction at 48 weeks, while 12mg achieved 24.2%, a difference of 1.4 percentage points

GLP-1 tablet in NIDDM in fasting and postprandial conditions

The change prevents DPP-IV cleaving the molecule, resulting in a previously unheard of half-life of a week

In vitro , AdipoRon treatment significantly lowered intracellular lipid accumulation in FE-challenged LMH cells while upregulating CPT-1 and PPAR expression, suggesting enhanced lipid catabolism and reduced lipid deposition