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Oxidative stress in DS is attributed to several genes on chromosome 21, including an extra copy of superoxide dismutase 1 (SOD1) 19
Youngren JF, Gable K, Penaranda C, Maddux BA, Zavodovskaya M, Lobo M et al (2005) Nordihydroguaiaretic acid (NDGA) inhibits the IGF-1 and c-erbB2/HER2/neu receptors and suppresses growth in breast Cancer cells
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