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From my perspective as a physician specializing in obesity medicine, GLP-1 medications like semaglutide have truly changed the game
For example, dual-agent nanoplatforms co-delivering BH3 mimetics with low-dose doxorubicin have been proposed to exploit mitochondrial priming and DNA damage simultaneously, enhancing apoptosis while reducing the dose-dependent cardiotoxicity of doxorubicin
Diabetes and Alzheimer disease, two overlapping pathologies with the same background: oxidative stress
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