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Where the dual-agonist signal shows up Adipose-tissue metabolism, insulin secretion dynamics, and gastrointestinal tolerability are the areas where GIP-R co-activation tends to produce results that GLP-1-only comparators do not replicate [2]
Researchers, however, noted that they observed no significant differences between groups in rates of ischemic stroke, acute myocardial infarction, and acute kidney injury
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