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The abrupt loss of oxidative phosphorylation impairs ATP-dependent ion pumps, causing rapid neuronal depolarization and the pathological accumulation of extracellular glutamate [2,3,4]
Unfortunately, glutathione levels decrease with age, stress, lack of proper diet, exposure to toxins, and diseases such as diabetes
Improving T21-Related Cognitive Impairments In Vitro Studies Currently, only a limited number of therapeutics and nutraceuticals have been examined using the Ts65Dn mouse model, which represents DS, with the objective of enhancing learning and memory functions (Galati et al
Proteinase-activated receptor-2 stimulates prostaglandin production in keratinocytes: analysis of prostaglandin receptors on human melanocytes and effects of PGE2 and PGF2alpha on melanocyte dendricity
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