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Nitroglycerin can exert vasodilation in the arteries at higher doses which results in a decrease in the pressure the heart must exert (termed afterload) to expel blood from the left ventricle, thereby, adding to reduced cardiac oxygen demand

The review emphasizes that future research should prioritize longitudinal human cohorts and intervention studies, together with controlled animal studies, that integrate precise exposure biomarkers with detailed immunological endpoints to refine species- and life-stage-specific intake guidelines

"Peptide Therapy in Medical Science: Advances and Challenges." Journal of Peptide Science, 26 (4), 112-124

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