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QUE exerts dose-dependent inhibition of drug-metabolizing enzymes and transporters in rats, significantly altering cyclosporine pharmacokinetics (89, 90)
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Oxygen is a crucial factor for human metabolism in general: oxidative phosphorylation, the role of multicopper oxidase enzyme (MCO) [16], arachidonic acid pathway - lipoxygenases (LOX), and cyclooxygenases (COX) -, and significantly, inflammatory pathway and particularly endothelial cells require molecular oxygen to be completed [17-19]
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A lay doctors guide to the inflammatory process in the gastrointestinal tract
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