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For patients with moderate renal insufficiency (CrCl greater than or equal to 30 to less than 50 mL/min, approximately corresponding to serum creatinine levels of greater than 1.7 to less than or equal to 3.0 mg/dL in men and greater than 1.5 to less than or equal to 2.5 mg/dL in women), the dose of Januvia is 50 mg once daily
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GLP-1 receptor activation produces the effects most people associate with medications like Ozempic and Wegovy
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