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Front Cell Dev Biol 10:950623

Stroke 38 , 22952302 (2007)

Control) or a high-fat diet (Harlan TD.88137, containing 42% calories as fat

In an experimental model, transgenic mice expressing a kinase-deficient IGF-1R -subunit (thus displaying reduced signal transduction in both IGF-1R and hybrid receptors) developed diabetes early on life [162, 236]