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J.HillT
[91] [92] There is also a hereditary genetic disease that involves mutations in the enzymes responsible for lysine catabolism, namely the bifunctional AASS enzyme of the saccharopine pathway
doi:10.1002/oby.24360
319,321 Collectively, the ability of HSP70 and HSP90 to engage multiple aggregation-prone client proteins across distinct NDDs underscores their central role in neuronal proteostasis and highlights their broad therapeutic potential
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