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A person can carry an MTHFR or COMT variant and still have adequate current methylation, while another person with no major variant can develop low SAM, elevated SAH or impaired glutathione production
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Glutathione conjugation of aflatoxin B1 exo- and endo-epoxides by rat and research [PMID: 1391613] Laboratory literature summary: Glutathione conjugation of aflatoxin B1 exo- and endo-epoxides by rat and research subjects glutathione S-transferases
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