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For stubborn belly fat specifically, strategies that address cortisol, insulin sensitivity, and sleep quality can move the needle significantly
Table 10
Supplementary information Supplementary Table 1 (download XLSX Sample sizes ( n ) and statistical significance values ( P values) for all data panels in the study
One of the most notable investigations, the STEP 1 trial published in The New England Journal of Medicine, reported that participants receiving weekly GLP1-S alongside lifestyle interventions experienced an average 14.9% decrease in body weight across 68 weeks[7][8]
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