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A network meta-analysis of 22 RCTs covering 2,258 participants found GLP-1 receptor agonists reduced lean mass by a mean of 0.86 kg, with lean mass comprising roughly 25% of total weight lost across agents

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GLP-1R regulates brain glucose metabolism The most prominent physiological effect of GLP-1 and GLP-1R is the regulation of insulin secretion in the pancreas to maintain postprandial glucose homeostasis, whereas outside the pancreas, GLP-1 and GLP-1R also regulate feeding and metabolism through the nervous system

However, the effect of NTAPP on hair growth or regeneration still remains unknown