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The authors thank Ai Miyashita, Miyuki Fujino, Nami Kitahara, Miho Nakamura, Yuki Nakashima, Mari Oda, Narumi Furuie, and Keiko Watanabe as RNs for their significant clinical care contributions

Although activation of the GLP-1 receptor primarily facilitates weight reduction through appetite suppression, the inclusion of GIP receptor agonism offers supplementary and synergistic advantages, including improved insulin sensitivity and overall metabolic health

Hernndez et al., 2017)

Many commonly prescribed medications, including beta blockers, corticosteroids, and opioids, can cause depressive symptoms by altering brain chemicals or affecting the central nervous system