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All dosing information here is provided strictly for research and laboratory reference
doi: 10.1155/2020/2624734 196 MooreJ
Accordingly, serine deprivation or SSP blockade restores the sensitivity of colorectal cancer cells to 5-FU ( 6.2.2 Targeted therapy resistance 6.2.2.1 BRAF inhibitor resistance Proteomic analysis of acquired-resistance cell lines revealed altered expression of serine biosynthetic enzymes (PHGDH, PSPH, PSAT1) in drug-resistant cells
Metabolite production was quantified by LC/MS/MS API3000 and normalized to total cell protein
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