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Anti-Inflammatory MC1R Signalling Pre-clinical research has identified MC1R-mediated anti-inflammatory pathways activated by MT-1 in keratinocyte and macrophage models, including NF-B suppression and anti-oxidant gene induction suggesting research utility beyond melanogenesis in inflammatory skin biology models
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Many online dosing protocols are based on anecdotal use rather than clinical-based evidence
The dropout rate was low (only 6 participants didnt finish the study), indicating the study was carefully conducted and had few severe side effects
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